| Date | Location | Result | |
| 02/28/06 | Ashland, OH (Kates Gymnasium) | Ashland 70, Mercyhurst 68 | Box score |
| 2/23/06 | Erie, Pa. - Hammermill Center | Gannon University 57, Mercyhurst College 54 | Box score |
| 02/18/06 | Erie, Pa. - Mercyhurst Athletic Center | Ashland 77, Mercyhurst 69 | Box score |
| 02/16/06 | Erie, Pa. - Mercyhurst Athletic Center | Findlay 60, Mercyhurst 47 | Box score |
| 2/11/06 | Jesse Philips Arena | Mercyhurst College 73, Hillsdale College 56 | Box score |
| 02/09/06 | Detroit, Mich./Matthaei | Mercyhurst 62, Wayne State Warriors 61 | Box score |
| 02/04/06 | Erie, Pa. - Mercyhurst Athletic Center | Mercyhurst 76, Michigan Tech 54 | Box score |
| 02/03/06 | Erie, Pa. - Mercyhurst Athletic Center | Mercyhurst 48, Northern Michigan 45 | Box score |
| 01/28/06 | Erie, Pa. - Mercyhurst Athletic Center | Mercyhurst 48, Gannon University 45 | Box score |
| 1-21-06 | Sault Ste. Marie, MI | Lake Superior State 96, Mercyhurst 94 | Box score |
| 1/19/06 | Big Rapids, Mich. | Mercyhurst 61, Ferris State 59 | Box score |
| 01/14/06 | Erie, Pa. - Mercyhurst Athletic Center | Mercyhurst 67, Saginaw Valley 63 | Box score |
| 01/07/06 | Erie, Pa. - Mercyhurst Athletic Center | Mercyhurst 69, Northwood 67 | Box score |
| 01/07/06 | Ashland, OH (Kates Gymnasium) | Ashland 79, Mercyhurst 68 | Box score |
| 1/5/06 | Findlay, Ohio | Findlay 73, Mercyhurst 43 | Box score |
| 12/30/05 | Ross Sports Center - Colchester, Vt. | Mercyhurst College 66, Concordia College 39 | Box score |
| 12/29/05 | Ross Sports Center - Colchester, Vt. | Mercyhurst College 70, Post University 47 | Box score |
| 12/20/05 | Shepherdstown, WV (Butcher Center) | Mercyhurst College 67, Shepherd University 54 | Box score |
| 12/17/05 | Erie, Pa. - Mercyhurst Athletic Center | Mercyhurst 75, Slippery Rock 43 | Box score |
| 12/10/05 | GVSU Fieldhouse Arena Allendale, Mich. | Grand Valley State 77, Mercyhurst College 52 | Box score |
| 12/07/05 | Erie, Pa. - Mercyhurst Athletic Center | Mercyhurst 76, Edinboro 72 | Box score |
| 12/03/05 | Erie, Pa./MAC | Mercyhurst 65, Wayne State 61 | Box score |
| 12/01/05 | Erie, Pa. - Mercyhurst Athletic Center | Hillsdale 63, Mercyhurst 52 | Box score |
| 11/27/05 | Erie, Pa. - Mercyhurst Athletic Center | Mercyhurst 90, Ohio Valley 58 | Box score |
| 11/22/05 | Mercyhurst Athletic Center - Erie, Pa. | Mercyhurst 69, Bloomsburg 48 | Box score |
| 11/19/05 | Merkert Gymnasium, Easton, Mass. | Mercyhurst 74, Molloy 72 | Box score |
| 11/18/05 | Merkert Gymnasium, Easton, Mass. | Mercyhurst 83, Felician 79 | Box score |
| 11/15/05 | Erie, Pa. - Mercyhurst Athletic Center | Mercyhurst 75, Notre Dame (Ohio) 62 | Box score |